God has been allowing crimes and injustices and blasphemies and abominations for so long, and he has been tolerating such lies and calumnies to be spoken about him all these years. Revelation 6 promises that one day the wrath will begin to fall. The debt finally comes due. Justice will be done. The wicked will give account. The righteous will be avenged. God will be glorified in his justice.

– James M. Hamilton, Jr. on Revelation 6 in Revelation (PTW)