Zophar bluntly tells Job that he is guilty and needs to repent.  Job responds by saying that God reigns over all and brings death to all.  Consider:

• God holds life – God holds the life of all in his hand (12:10). He has numbered our days (14:5).  We exist by his power and will.  Let us flee proud thoughts of our own sufficiency, and let us humble ourselves before our Creator.
• God’s wisdom – God has wisdom, counsel, and understanding, and he has might to carry out his wise plans (12:13). In the midst of trials, will we trust his wisdom instead of leaning on our own understanding?